Protein Polymer Technologies Reports Third Quarter Financial Results

    SAN DIEGO, Nov. 6 -- Protein Polymer Technologies, Inc. (Nasdaq: PPTI), reports today its financial results for the third quarter and nine months ended September 30, 1998.
    For the quarter, the Company had a net loss applicable to common shareholders of $1,529,000 ($.14 a share), versus a net loss of $1,268,000 ($.14 a share) for the comparable period in 1997.  For the nine months ended September 30, 1998, the Company's financial results include, as is required by the Securities and Exchange Commission, the one-time, non-cash "imputed dividends" of $3,266,000 from the sale and issuance of the Company's Series E Preferred Convertible stock, which raised approximately $5.4 million in April and May.  Including the imputed dividends, the Company had a net loss applicable to common shareholders of $7,662,000 ($.73 a share) for the nine months ended September 30, 1998, versus a net loss of $3,570,000 ($.39 a share) for the same period in 1997.  Excluding the effect of the imputed dividends, the net loss applicable to common shareholders would have been $4,396,000 ($.42 per share) for the nine months ended September 30, 1998.
    Operating expenses for the quarter were $1,508,000 as compared to $1,311,000 for the same period in 1997.  For the nine months ended September 30, 1998, operating expenses totaled $4,368,000 compared to $3,758,000 for the same period in 1997.  The increased expenditures were due to increased regulatory activity and preclinical testing in preparation for clinical testing of the Company's soft tissue augmentation products.  Contract revenues, interest and product income totaled $48,000 for the quarter, compared to $161,000 for the same period in 1997.  For the nine months ended September 30, 1998, these revenues totaled $181,000, compared to $549,000 for the same period in 1997.  The decreases were due to reduced contract revenues and interest income.  The cash balance was $2,560,000 as of September 30, 1998, compared to $1,300,000 as of December 31, 1997.
    "Our financial results for the third quarter and first nine months of 1998 reflect our expanding commitment to the development and registration of our soft tissue augmentation products," said J. Thomas Parmeter, PPTI's President and Chief Executive Officer.  "We expect to continue to spend at this level or higher, to the extent capital is available, as we prepare to file Investigational Device Exemptions (IDE) with the U.S. Food and Drug Administration (FDA) and begin human clinical studies for both the female stress urinary incontinence indication and for cosmetic applications."
    "Our strategy has been to develop our potential products in-house until sufficient shareholder value can be obtained from a strategic partnering relationship.  We are currently in discussions with a number of potential partners regarding these soft tissue augmentation applications and for tissue adhesive product opportunities."
    Protein Polymer Technologies, Inc., is a San Diego-based company focused on developing products to improve medical and surgical outcomes.  From its inception in 1988, PPTI has been a pioneer in protein design and synthesis, developing an extensive portfolio of proprietary biomaterials.  These genetically engineered biomaterials are high molecular weight proteins, processed into products with physical and biological characteristics tailored to specific clinical performance requirements.  Targeted products include urethral bulking agents for the treatment of stress urinary incontinence, dermal augmentation products for cosmetic and reconstructive surgery, tissue adhesives and sealants, scaffolds for wound healing and tissue engineering, and depots for local drug delivery.
    This press release may contain forward-looking statements that are based on management's expectations.  Actual results could differ materially from those expressed here; further, the Company is not obligated to comment specifically on those differences.  Risks associated with the Company's activities include scientific and product development uncertainties, competitive products and approaches, continuing collaborative partnership interest and funding, regulatory testing and approvals, and manufacturing scale-up.  The reader is encouraged to refer to the Company's 1997 Annual Report and 10-KSB, and recent filings with the Securities and Exchange Commission, copies of which are available from the Company, to further ascertain the risks associated with the above statements.

                      Protein Polymer Technologies, Inc.
                        Condensed Financial Statements
                                 (unaudited)

                               Three months ended        Nine months ended
                                  September 30,            September 30,

    SUMMARY OF OPERATIONS       1998          1997         1998         1997

    Contract revenue             $--       $91,510      $50,000     $324,510
    Interest income           41,771        41,151       90,336      162,885
    Product and
     other income              6,725        27,840       41,020       61,744
        Total revenues        48,496       160,501      181,356      549,139

    Total expenses         1,508,172     1,311,291    4,368,486    3,757,851

    Net loss             $(1,459,676)  $(1,150,790) $(4,187,130) $(3,208,712)

    Undeclared, imputed
     and/or paid
     dividends on
     Preferred Stock          69,410       117,657    3,474,913      361,569

    Net loss applicable
     to common
     shareholders        $(1,529,086)  $(1,268,447) $(7,662,043) $(3,570,281)

    Net loss per
     common share -
     basic and diluted       $(0.14)        $(0.14)      $(0.73)     $(0.39)

    Shares used in
     computing net loss
     per share - basic
     and diluted          10,575,811     9,332,156   10,492,508    9,173,040


                                      As of                  As of
                                  Sept. 30, 1998         Dec. 31, 1997
                                                          (audited)

    BALANCE SHEET INFORMATION
    Cash, cash equivalents and
    short-term investments         $2,560,460            $1,299,838
    Working capital                 1,973,867               697,020
    Total assets                    3,491,690             2,347,887
    Total capital invested         34,248,515            25,549,644
    Accumulated deficit           (31,536,890)          (24,083,511)




CONTACT:
J. Thomas Parmeter, President/CEO
Lisa Swann, Director, Investor Relations
619-558-6064
info@ppti.com



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