| United States Patent | 5,770,697 |
| Ferrari, et. al. | Jun. 23, 1998 |
| Inventors: | Ferrari; Franco A. (La Jolla, CA); Richardson; Charles (Florence, MT); Chambers; James (San Diego, CA); Causey; Stuart (Palo Alto, CA); Pollock; Thomas J. (San Diego, CA); Cappello; Joseph (San Diego, CA); Crissman; John W. (San Diego, CA). |
| Assignee: | Protein Polymer Technologies, Inc. (San Diego, CA). |
| Appl. No.: | 477,509 |
| Filed: | Jun. 7, 1995 |
| Intl. Cl. : | A61K 38/17, A61K 38/39, C12P 21/02 |
| Current U.S. Cl.: | 530/353; 435/69.1; 530/356; 530/357 |
| Field of Search: | 435/69.1; 530/353, 356, 357 |
| 4,132,746 | Jan., 1979 | Urry et al. | 525/432 |
| 4,187,852 | Feb., 1980 | Urry et al. | 600/36 |
| 4,474,851 | Oct., 1984 | Urry | 428/373 |
| 4,500,700 | Feb., 1985 | Urry | 528/328 |
| 4,589,882 | May, 1986 | Urry | 623/11 |
| 5,089,406 | Feb., 1992 | Williams et al. | 435/172.3 |
| 5,149,657 | Sept., 1992 | Maugh et al. | 435/320.1 |
| 2162190A | Jan., 1986 | GB |
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Primary Examiner: Ketter; James
Assistant Examiner: Brusca; John S.
Attorney, Agent or Firm: Trecartin; Richard F.
Novel polypeptides comprising repetitive units of amino acids, as well as synthetic genes encoding the subject polypeptides are provided. The subject polypeptides are characterized by comprising repetitive units of amino acids, where the repetitive units are present in naturally occurring proteins, particularly naturally occurring structural proteins. The subject polypeptides find use in a variety of applications, such as structural components of prosthetic devices, synthetic fibers, and the like.
The government has certain rights in this invention as a result of support provided by the Department of the Navy for the work leading to the present invention.
